We are looking for individuals between the ages of 20 -75 who are diagnosed with painful diabetic neuropathy. This study looks at the effects of brain stimulation on pain perception for individuals who suffer from painful diabetic neuropathy.
You will be asked to fill out a series of questionnaires, donate a saliva sample, and receive brain stimulation by Controlled Pulse Parameter Transcranial magnetic stimulation (cTMS) to the motor areas of the brain.
For more information about this study, or to volunteer for this study, please contact
Jiyeon Park at parkj103@mcmaster.ca
This study has been reviewed by, and received ethics clearance by the
Hamilton Integrated Research Ethics Board (HIREB) under project #16481.
How can cTMS be use to alleviate pain in painful diabetic neuropathy?
How does the brain react to cTMS to alleviate pain?
This study will investigate the effects of 10-day cTMS on pain symptoms. It will also look at how the brain reacts to cTMS after 10-days of intervention, exploring a new potential treatment option to manage painful diabetic neuropathy!
This study is among the first of it’s kind to study how cTMS can be used to help manage pain.
Your participation can help us further study the effect of cTMS on the brain, to explore it as a potential treatment for diabetic neuropathy!
Your participation in our study can help us explore the potential of using cTMS as a treatment option to alleviate pain in painful diabetic neuropathy! Your role is simple:
2 weeks of
questionnaires
Nerve Assessment,
and a Saliva Sample
(pre-intervention)
10 sessions of cTMS
over 2 weeks
(30 minutes each)
(Intervention)
Nerve Assessments
(post-intervention)
2 weeks of
questionnaires
Wait 2 Months
(wash out period)
Repeat without the
saliva sample!
Painful Diabetic Neuropathy is a condition in which individuals with chronically high blood sugar levels (usually diabetic patients) can lead to damage of nerve endings. Sometimes, this damage can cause pain.
The pain signals from these damaged nerve endings is processed in the brain. We aim to stimulate brain cells using cTMS to see if it can help minimize these pain signals – reducing the pain felt.
Controllable Pulse Parameter Transcranial Magnetic Stimulation (cTMS) is a non-invasive technique used to stimulate certain brain cells from the outside. The cTMS works by generating a magnetic field through it’s coils, which induces an electric current stimulating certain brain cells.
In this study, cTMS will be used to record how the brain reacts to pain over 2 weeks, and after 2 months!
Dr. Aimee Nelson
Phone: 905 525 9140 ext. 28053
E-mail: nelsonaj@mcmaster.ca
Office: IWC E208
Ivor Wynne Centre
AB 131, AB 126
McMaster University
Hamilton, ON L8S 4K1
Ivor Wynne Centre
AB 131, AB 126
McMaster University
Hamilton, ON L8S 4K1